Drug interactions
Caspofungin + Voclosporin
Severity: Minor
Caspofungin and Voclosporin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voclosporin is a calcineurin inhibitor with dose-related nephrotoxicity. Caspofungin is not a recognized nephrotoxin, so any additive renal harm is theoretical, but renal function matters in patients on voclosporin.
What this interaction means in plain words
Caspofungin and Voclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Caspofungin belongs to Anti Fungals; Voclosporin belongs to Miscellaneous.
Why it happens
No established mechanism; additive nephrotoxicity is only theoretical.
What to do
Monitor serum creatinine and eGFR as is routine for voclosporin, and reduce the voclosporin dose per labeling if renal function declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Caspofungin
- Apalutamide + Caspofungin Moderate
- Carbamazepine + Caspofungin Moderate
- Caspofungin + Cyclosporin Moderate
- Caspofungin + Dexamethasone Moderate
- Caspofungin + Efavirenz Moderate
- Caspofungin + Fosphenytoin Moderate
Other interactions of Voclosporin
- Clarithromycin + Voclosporin Contraindicated
- Cyclosporin + Voclosporin Contraindicated
- Ensitrelvir + Voclosporin Contraindicated
- Itraconazole + Voclosporin Contraindicated
- Ketoconazole + Voclosporin Contraindicated
- Posaconazole + Voclosporin Contraindicated
Frequently asked questions
Can I take Caspofungin with Voclosporin?
MediHelp rates the interaction as minor. Caspofungin and Voclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voclosporin is a calcineurin inhibitor with dose-related nephrotoxicity. Caspofungin is not a recognized nephrotoxin, so any additive renal harm is theoretical, but renal function matters in patients on voclosporin.
How serious is the interaction between Caspofungin and Voclosporin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and eGFR as is routine for voclosporin, and reduce the voclosporin dose per labeling if renal function declines.
What other medicines interact with Caspofungin?
MediHelp also lists interactions of Caspofungin with, for example, Apalutamide, Carbamazepine, Cyclosporin. The full list is on the Caspofungin page.
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