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Drug interactions

Cefditoren + Erythromycin

Severity: Minor

Cefditoren and Erythromycin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Macrolide bacteriostatic activity could theoretically blunt the bactericidal effect of a beta-lactam that depends on actively dividing bacteria. Clinical evidence of reduced cure rates is limited and inconsistent.

What this interaction means in plain words

Cefditoren and Erythromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cefditoren belongs to Anti Bacterial; Erythromycin belongs to Anti Bacterial.

Evidence level: Low

Why it happens

Theoretical pharmacodynamic antagonism between a protein synthesis inhibitor and a cell-wall-active bactericidal agent.

What to do

No routine change is needed; if treating a severe infection such as meningitis or endocarditis, avoid unnecessary combination and review the indication for each agent.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cefditoren with Erythromycin?

MediHelp rates the interaction as minor. Cefditoren and Erythromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Macrolide bacteriostatic activity could theoretically blunt the bactericidal effect of a beta-lactam that depends on actively dividing bacteria. Clinical evidence of reduced cure rates is limited and inconsistent.

How serious is the interaction between Cefditoren and Erythromycin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; if treating a severe infection such as meningitis or endocarditis, avoid unnecessary combination and review the indication for each agent.

What other medicines interact with Erythromycin?

MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.

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