Drug interactions
Cefotetan + Furosemide
Severity: Minor
Cefotetan and Furosemide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cephalosporins may add to the nephrotoxic potential of loop diuretics, particularly with volume depletion or renal impairment. Evidence for cefotetan is limited and the risk is mainly in vulnerable patients.
What this interaction means in plain words
Cefotetan and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefotetan belongs to Anti Bacterial; Furosemide belongs to Cardiovascular.
Why it happens
Possible additive renal tubular injury, aggravated by diuretic-induced volume depletion.
What to do
Monitor serum creatinine in patients who are volume depleted or have renal impairment, and keep them well hydrated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cefotetan and Furosemide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Other interactions of Cefotetan
- Cefotetan + Dronabinol Contraindicated
- Cefotetan + Warfarin Major
- Amikacin + Cefotetan Moderate
- Argatroban + Cefotetan Moderate
- Cefotetan + Dalteparin Moderate
- Cefotetan + Enoxaparin Moderate
Frequently asked questions
Can I take Cefotetan with Furosemide?
MediHelp rates the interaction as minor. Cefotetan and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cephalosporins may add to the nephrotoxic potential of loop diuretics, particularly with volume depletion or renal impairment. Evidence for cefotetan is limited and the risk is mainly in vulnerable patients.
How serious is the interaction between Cefotetan and Furosemide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine in patients who are volume depleted or have renal impairment, and keep them well hydrated.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
