Drug interactions
Cefpirome + Chlorpropamide
Severity: Minor
Cefpirome and Chlorpropamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are organic acids that may compete for renal tubular secretion, which could in theory slightly raise chlorpropamide exposure. No meaningful clinical effect has been established.
What this interaction means in plain words
Cefpirome and Chlorpropamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefpirome belongs to Anti Bacterial; Chlorpropamide belongs to Endocrine.
Why it happens
Theoretical competition for renal tubular anionic secretion.
What to do
No specific action is needed; monitor blood glucose if the patient shows signs of hypoglycemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlorpropamide
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Cefpirome with Chlorpropamide?
MediHelp rates the interaction as minor. Cefpirome and Chlorpropamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are organic acids that may compete for renal tubular secretion, which could in theory slightly raise chlorpropamide exposure. No meaningful clinical effect has been established.
How serious is the interaction between Cefpirome and Chlorpropamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor blood glucose if the patient shows signs of hypoglycemia.
What other medicines interact with Chlorpropamide?
MediHelp also lists interactions of Chlorpropamide with, for example, Ethanol, Exenatide, Insulin degludec-insulin aspart. The full list is on the Chlorpropamide page.
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