Drug interactions
Cefpirome + Meclofenamic acid
Severity: Minor
Cefpirome and Meclofenamic acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefpirome is renally eliminated in part by tubular secretion and may slightly reduce meclofenamic acid clearance. Any clinical effect is expected to be small.
What this interaction means in plain words
Cefpirome and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefpirome belongs to Anti Bacterial; Meclofenamic acid belongs to Musculoskeletal.
Why it happens
Competition for renal tubular organic anion secretion.
What to do
No specific action needed; monitor for NSAID adverse effects in patients with impaired renal function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Meclofenamic acid
- Ketorolac intranasal + Meclofenamic acid Contraindicated
- Ketorolac + Meclofenamic acid Contraindicated
- Aceclofenac + Meclofenamic acid Major
- Acemetacin + Meclofenamic acid Major
- Alteplase + Meclofenamic acid Major
- Amiloride + Meclofenamic acid Major
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Cefpirome with Meclofenamic acid?
MediHelp rates the interaction as minor. Cefpirome and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefpirome is renally eliminated in part by tubular secretion and may slightly reduce meclofenamic acid clearance. Any clinical effect is expected to be small.
How serious is the interaction between Cefpirome and Meclofenamic acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action needed; monitor for NSAID adverse effects in patients with impaired renal function.
What other medicines interact with Meclofenamic acid?
MediHelp also lists interactions of Meclofenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meclofenamic acid page.
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