Drug interactions
Ceritinib + Formoterol-mometasone
Severity: Minor
Ceritinib and Formoterol-mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ceritinib can raise blood glucose, and corticosteroids also cause hyperglycemia. Inhaled mometasone has low systemic exposure, but formoterol may add a small glucose-raising effect, so glycemic control could worsen in susceptible patients. The legacy hint of increased hypoglycemia is the opposite of the expected direction.
What this interaction means in plain words
Ceritinib and Formoterol-mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ceritinib belongs to Oncology; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive pharmacodynamic hyperglycemic effects of ceritinib, corticosteroid and beta-agonist.
What to do
Monitor blood glucose in diabetic or prediabetic patients on ceritinib who use this inhaler regularly, and adjust antidiabetic therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Formoterol-mometasone
Other interactions of Ceritinib
- Ceritinib + Cisapride Contraindicated
- Ceritinib + Eletriptan Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Ceritinib + Pimozide Contraindicated
- Ceritinib + Thioridazine Contraindicated
- Ceritinib + Tolvaptan Contraindicated
Frequently asked questions
Can I take Ceritinib with Formoterol-mometasone?
MediHelp rates the interaction as minor. Ceritinib and Formoterol-mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ceritinib can raise blood glucose, and corticosteroids also cause hyperglycemia. Inhaled mometasone has low systemic exposure, but formoterol may add a small glucose-raising effect, so glycemic control could worsen in susceptible patients. The legacy hint of increased hypoglycemia is the opposite of the expected direction.
How serious is the interaction between Ceritinib and Formoterol-mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose in diabetic or prediabetic patients on ceritinib who use this inhaler regularly, and adjust antidiabetic therapy if control worsens.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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