Drug interactions
Chlorthalidone + Verteporfin
Severity: Minor
Chlorthalidone and Verteporfin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chlorthalidone is a photosensitizing drug and may add to the photosensitivity reactions seen after verteporfin photodynamic therapy. Patients could develop exaggerated sunburn-like skin reactions on exposure to light.
What this interaction means in plain words
Chlorthalidone and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chlorthalidone belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.
Why it happens
Additive photosensitization from two drugs that can sensitize skin to light.
What to do
Counsel patients to follow verteporfin light-avoidance precautions strictly for the period specified in labeling and to protect skin and eyes from sunlight.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlorthalidone
Other interactions of Verteporfin
- Doxycycline + Verteporfin Moderate
- Griseofulvin + Verteporfin Moderate
- Minocycline + Verteporfin Moderate
- Tetracycline + Verteporfin Moderate
- Adapalene + Verteporfin Minor
- Amlodipine-hydrochlorothiazide-valsartan + Verteporfin Minor
Frequently asked questions
Can I take Chlorthalidone with Verteporfin?
MediHelp rates the interaction as minor. Chlorthalidone and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chlorthalidone is a photosensitizing drug and may add to the photosensitivity reactions seen after verteporfin photodynamic therapy. Patients could develop exaggerated sunburn-like skin reactions on exposure to light.
How serious is the interaction between Chlorthalidone and Verteporfin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to follow verteporfin light-avoidance precautions strictly for the period specified in labeling and to protect skin and eyes from sunlight.
What other medicines interact with Chlorthalidone?
MediHelp also lists interactions of Chlorthalidone with, for example, Amifostine, Atenolol-chlorthalidone, Candesartan-hydrochlorothiazide. The full list is on the Chlorthalidone page.
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