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Drug interactions

Ciclesonide + Danazol

Severity: Minor

Ciclesonide and Danazol: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Danazol inhibits CYP3A4 and may raise exposure to ciclesonide's active metabolite. Systemic corticosteroid effects are possible with prolonged use.

What this interaction means in plain words

Ciclesonide and Danazol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Danazol inhibits CYP3A4-mediated metabolism of ciclesonide.

What to do

Monitor for systemic corticosteroid effects during long-term co-use and use the lowest effective ciclesonide dose.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ciclesonide with Danazol?

MediHelp rates the interaction as minor. Ciclesonide and Danazol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol inhibits CYP3A4 and may raise exposure to ciclesonide's active metabolite. Systemic corticosteroid effects are possible with prolonged use.

How serious is the interaction between Ciclesonide and Danazol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for systemic corticosteroid effects during long-term co-use and use the lowest effective ciclesonide dose.

What other medicines interact with Ciclesonide?

MediHelp also lists interactions of Ciclesonide with, for example, Ritonavir, Apalutamide, Atazanavir. The full list is on the Ciclesonide page.

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