Drug interactions
Cilostazol + Methylprednisolone
Severity: Minor
Cilostazol and Methylprednisolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may weakly induce CYP3A4, which could reduce cilostazol exposure, though clinical significance is unproven.
What this interaction means in plain words
Cilostazol and Methylprednisolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cilostazol belongs to Cardiovascular; Methylprednisolone belongs to Endocrine.
Why it happens
Possible weak CYP3A4 induction increasing cilostazol metabolism.
What to do
No dose change is required; monitor claudication symptom response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Methylprednisolone
- Bcg vaccine live + Methylprednisolone Contraindicated
- Measles mumps and rubella vaccine live + Methylprednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Methylprednisolone Contraindicated
- Measles vaccine + Methylprednisolone Contraindicated
- Methylprednisolone + Mifepristone Contraindicated
- Methylprednisolone + Rubella vaccine Contraindicated
Other interactions of Cilostazol
Frequently asked questions
Can I take Cilostazol with Methylprednisolone?
MediHelp rates the interaction as minor. Cilostazol and Methylprednisolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids may weakly induce CYP3A4, which could reduce cilostazol exposure, though clinical significance is unproven.
How serious is the interaction between Cilostazol and Methylprednisolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is required; monitor claudication symptom response.
What other medicines interact with Methylprednisolone?
MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Methylprednisolone page.
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