Drug interactions
Cimetidine + Oteseconazole
Severity: Minor
Cimetidine and Oteseconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oteseconazole inhibits BCRP and could raise exposure to BCRP substrates. Cimetidine is a weak BCRP substrate, so any clinically relevant rise is unlikely.
What this interaction means in plain words
Cimetidine and Oteseconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cimetidine belongs to Gastrointestinal Tract; Oteseconazole belongs to Anti Fungals.
Why it happens
Oteseconazole inhibits the BCRP efflux transporter, potentially reducing cimetidine efflux.
What to do
No routine action is needed; consider reducing the cimetidine dose only if adverse effects appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cimetidine
- Cimetidine + Dofetilide Contraindicated
- Cimetidine + Fezolinetant Contraindicated
- Alfentanil + Cimetidine Major
- Atazanavir + Cimetidine Major
- Carmustine + Cimetidine Major
- Cimetidine + Citalopram Major
Other interactions of Oteseconazole
- Atorvastatin + Oteseconazole Moderate
- Fluvastatin + Oteseconazole Moderate
- Glibenclamide + Oteseconazole Moderate
- Glyburide-metformin + Oteseconazole Moderate
- Irinotecan + Oteseconazole Moderate
- Lapatinib + Oteseconazole Moderate
Frequently asked questions
Can I take Cimetidine with Oteseconazole?
MediHelp rates the interaction as minor. Cimetidine and Oteseconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oteseconazole inhibits BCRP and could raise exposure to BCRP substrates. Cimetidine is a weak BCRP substrate, so any clinically relevant rise is unlikely.
How serious is the interaction between Cimetidine and Oteseconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; consider reducing the cimetidine dose only if adverse effects appear.
What other medicines interact with Cimetidine?
MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.
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