Drug interactions
Cinacalcet + Eslicarbazepine
Severity: Minor
Cinacalcet and Eslicarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eslicarbazepine may modestly lower cinacalcet exposure through weak CYP3A4 induction. This could reduce the calcium or PTH lowering effect.
What this interaction means in plain words
Cinacalcet and Eslicarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cinacalcet belongs to Miscellaneous; Eslicarbazepine belongs to Central Nervous System.
Why it happens
Eslicarbazepine weakly induces CYP3A4, increasing cinacalcet metabolism.
What to do
Monitor serum calcium and PTH after starting or stopping eslicarbazepine and adjust cinacalcet if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eslicarbazepine
- Eslicarbazepine + Mavacamten Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Eslicarbazepine Major
- Avapritinib + Eslicarbazepine Major
- Bedaquiline + Eslicarbazepine Major
- Benzhydrocodone / acetaminophen + Eslicarbazepine Major
Other interactions of Cinacalcet
- Cinacalcet + Etelcalcetide Contraindicated
- Cinacalcet + Eliglustat Major
- Cinacalcet + Metoclopramide Major
- Cinacalcet + Metoclopramide intranasal Major
- Cinacalcet + Tamoxifen Major
- Abiraterone + Cinacalcet Moderate
Frequently asked questions
Can I take Cinacalcet with Eslicarbazepine?
MediHelp rates the interaction as minor. Cinacalcet and Eslicarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eslicarbazepine may modestly lower cinacalcet exposure through weak CYP3A4 induction. This could reduce the calcium or PTH lowering effect.
How serious is the interaction between Cinacalcet and Eslicarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and PTH after starting or stopping eslicarbazepine and adjust cinacalcet if needed.
What other medicines interact with Eslicarbazepine?
MediHelp also lists interactions of Eslicarbazepine with, for example, Mavacamten, Rilpivirine, Artemether / lumefantrine. The full list is on the Eslicarbazepine page.
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