Drug interactions
Ciprofloxacin + Mometasone
Severity: Minor
Ciprofloxacin and Mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoroquinolones carry a risk of tendinopathy and tendon rupture that is increased by systemic corticosteroids. With inhaled mometasone the systemic exposure is low, so the added risk is likely small.
What this interaction means in plain words
Ciprofloxacin and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ciprofloxacin belongs to Anti Bacterial; Mometasone belongs to Respiratory.
Why it happens
Additive tendon toxicity of fluoroquinolones and corticosteroids; relevance reduced with low systemic exposure from inhalation.
What to do
Advise patients to stop the quinolone and report tendon pain or swelling promptly. Take extra care in older patients or those on high-dose or systemic steroids.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mometasone
- Mometasone + Ritonavir Major
- Atazanavir + Mometasone Moderate
- Clarithromycin + Mometasone Moderate
- Cobicistat + Mometasone Moderate
- Darunavir + Mometasone Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Mometasone Moderate
Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Frequently asked questions
Can I take Ciprofloxacin with Mometasone?
MediHelp rates the interaction as minor. Ciprofloxacin and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluoroquinolones carry a risk of tendinopathy and tendon rupture that is increased by systemic corticosteroids. With inhaled mometasone the systemic exposure is low, so the added risk is likely small.
How serious is the interaction between Ciprofloxacin and Mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to stop the quinolone and report tendon pain or swelling promptly. Take extra care in older patients or those on high-dose or systemic steroids.
What other medicines interact with Mometasone?
MediHelp also lists interactions of Mometasone with, for example, Ritonavir, Atazanavir, Clarithromycin. The full list is on the Mometasone page.
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