Drug interactions
Ciprofloxacin + Stiripentol
Severity: Minor
Ciprofloxacin and Stiripentol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Stiripentol inhibits P-glycoprotein in vitro and could modestly raise ciprofloxacin exposure. The clinical impact is probably small.
What this interaction means in plain words
Ciprofloxacin and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ciprofloxacin belongs to Anti Bacterial; Stiripentol belongs to Central Nervous System.
Why it happens
Possible inhibition of P-glycoprotein efflux of ciprofloxacin by stiripentol.
What to do
No routine dose change is needed. Monitor for ciprofloxacin adverse effects, including CNS effects, in patients with epilepsy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Stiripentol
Frequently asked questions
Can I take Ciprofloxacin with Stiripentol?
MediHelp rates the interaction as minor. Ciprofloxacin and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Stiripentol inhibits P-glycoprotein in vitro and could modestly raise ciprofloxacin exposure. The clinical impact is probably small.
How serious is the interaction between Ciprofloxacin and Stiripentol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed. Monitor for ciprofloxacin adverse effects, including CNS effects, in patients with epilepsy.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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