Drug interactions
Clarithromycin + Eslicarbazepine
Severity: Minor
Clarithromycin and Eslicarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eslicarbazepine is a weak inducer of CYP3A4 and may modestly lower clarithromycin concentrations. The effect is probably small, though reduced antibacterial efficacy is possible in serious infections.
What this interaction means in plain words
Clarithromycin and Eslicarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clarithromycin belongs to Anti Bacterial; Eslicarbazepine belongs to Central Nervous System.
Why it happens
Weak induction of CYP3A4 by eslicarbazepine increases clarithromycin metabolism.
What to do
No routine adjustment is needed; watch for inadequate clinical response to clarithromycin in severe infections and consider an alternative antibiotic if response is poor.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clarithromycin
- Astemizole + Clarithromycin Contraindicated
- Avanafil + Clarithromycin Contraindicated
- Cisapride + Clarithromycin Contraindicated
- Clarithromycin + Colchicine Contraindicated
- Clarithromycin + Conivaptan Contraindicated
- Clarithromycin + Dihydroergotamine Contraindicated
Other interactions of Eslicarbazepine
- Eslicarbazepine + Mavacamten Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Eslicarbazepine Major
- Avapritinib + Eslicarbazepine Major
- Bedaquiline + Eslicarbazepine Major
- Benzhydrocodone / acetaminophen + Eslicarbazepine Major
Frequently asked questions
Can I take Clarithromycin with Eslicarbazepine?
MediHelp rates the interaction as minor. Clarithromycin and Eslicarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eslicarbazepine is a weak inducer of CYP3A4 and may modestly lower clarithromycin concentrations. The effect is probably small, though reduced antibacterial efficacy is possible in serious infections.
How serious is the interaction between Clarithromycin and Eslicarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; watch for inadequate clinical response to clarithromycin in severe infections and consider an alternative antibiotic if response is poor.
What other medicines interact with Clarithromycin?
MediHelp also lists interactions of Clarithromycin with, for example, Astemizole, Avanafil, Cisapride. The full list is on the Clarithromycin page.
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