Drug interactions
Clemastine + Hawthorn
Severity: Minor
Clemastine and Hawthorn: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has mild sedative and cardiovascular effects, and a theoretical additive effect with sedating antihistamines has been suggested. Clinical evidence for a meaningful interaction with clemastine is limited.
What this interaction means in plain words
Clemastine and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clemastine belongs to Respiratory; Hawthorn belongs to Gastrointestinal Tract.
Why it happens
Possible additive sedation; the mechanism is not well established.
What to do
No routine adjustment is needed. Advise the patient to report excess drowsiness and avoid driving if affected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clemastine
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Clemastine with Hawthorn?
MediHelp rates the interaction as minor. Clemastine and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn has mild sedative and cardiovascular effects, and a theoretical additive effect with sedating antihistamines has been suggested. Clinical evidence for a meaningful interaction with clemastine is limited.
How serious is the interaction between Clemastine and Hawthorn?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Advise the patient to report excess drowsiness and avoid driving if affected.
What other medicines interact with Clemastine?
MediHelp also lists interactions of Clemastine with, for example, Alfentanil, Benzhydrocodone / acetaminophen, Buprenorphine buccal. The full list is on the Clemastine page.
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