Drug interactions
Amiodarone + Hawthorn
Severity: Moderate
Amiodarone and Hawthorn: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has cardioactive effects including vasodilation, positive inotropy and possible antiarrhythmic activity. It might add to amiodarone's effects on heart rate, conduction and blood pressure, but good clinical data are lacking.
What this interaction means in plain words
Amiodarone and Hawthorn can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amiodarone belongs to Cardiovascular; Hawthorn belongs to Gastrointestinal Tract.
Why it happens
Possible additive cardiovascular pharmacodynamic effects; the mechanism is not well established.
What to do
Advise patients to avoid hawthorn supplements unless supervised. If used, monitor heart rate, blood pressure and ECG.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Other interactions of Hawthorn
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
- Hawthorn + Propranolol Moderate
Frequently asked questions
Can I take Amiodarone with Hawthorn?
MediHelp rates the interaction as moderate. Amiodarone and Hawthorn can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hawthorn has cardioactive effects including vasodilation, positive inotropy and possible antiarrhythmic activity. It might add to amiodarone's effects on heart rate, conduction and blood pressure, but good clinical data are lacking.
How serious is the interaction between Amiodarone and Hawthorn?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid hawthorn supplements unless supervised. If used, monitor heart rate, blood pressure and ECG.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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