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Drug interactions

Encainide + Hawthorn

Severity: Moderate

Encainide and Hawthorn: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Hawthorn has cardioactive properties that could theoretically alter the effects of class IC antiarrhythmics. Encainide is proarrhythmic and rarely used today.

What this interaction means in plain words

Encainide and Hawthorn can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Theoretical additive cardiac electrophysiologic effects; not well characterized.

What to do

Avoid hawthorn if possible; otherwise monitor ECG and symptoms of arrhythmia.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Encainide with Hawthorn?

MediHelp rates the interaction as moderate. Encainide and Hawthorn can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hawthorn has cardioactive properties that could theoretically alter the effects of class IC antiarrhythmics. Encainide is proarrhythmic and rarely used today.

How serious is the interaction between Encainide and Hawthorn?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid hawthorn if possible; otherwise monitor ECG and symptoms of arrhythmia.

What other medicines interact with Hawthorn?

MediHelp also lists interactions of Hawthorn with, for example, Amiodarone, Digoxin, Disopyramide. The full list is on the Hawthorn page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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