Drug interactions
Hawthorn + Procainamide
Severity: Moderate
Hawthorn and Procainamide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has cardioactive properties and could theoretically modify the effects of procainamide, which can prolong QRS and QT and cause arrhythmias.
What this interaction means in plain words
Hawthorn and Procainamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Theoretical additive cardiac electrophysiologic effects; not well characterized.
What to do
Monitor ECG and blood pressure if both are used, or advise avoiding the herb.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Propranolol Moderate
Frequently asked questions
Can I take Hawthorn with Procainamide?
MediHelp rates the interaction as moderate. Hawthorn and Procainamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hawthorn has cardioactive properties and could theoretically modify the effects of procainamide, which can prolong QRS and QT and cause arrhythmias.
How serious is the interaction between Hawthorn and Procainamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and blood pressure if both are used, or advise avoiding the herb.
What other medicines interact with Hawthorn?
MediHelp also lists interactions of Hawthorn with, for example, Amiodarone, Digoxin, Disopyramide. The full list is on the Hawthorn page.
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