Drug interactions
Disopyramide + Hawthorn
Severity: Moderate
Disopyramide and Hawthorn: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has cardioactive properties and could theoretically modify the electrophysiologic effects of antiarrhythmics. Disopyramide has a narrow therapeutic window with proarrhythmic and negative inotropic risk.
What this interaction means in plain words
Disopyramide and Hawthorn can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Disopyramide belongs to Cardiovascular; Hawthorn belongs to Gastrointestinal Tract.
Why it happens
Theoretical additive cardiac electrophysiologic and hemodynamic effects; not well characterized.
What to do
Monitor ECG and blood pressure if hawthorn is used with disopyramide, or advise avoiding the herb.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Disopyramide and Hawthorn, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
- Hawthorn + Propranolol Moderate
Other interactions of Disopyramide
- Amisulpride + Disopyramide Contraindicated
- Desipramine + Disopyramide Contraindicated
- Disopyramide + Dronedarone Contraindicated
- Disopyramide + Itraconazole Contraindicated
- Disopyramide + Ketoconazole Contraindicated
- Disopyramide + Maprotiline Contraindicated
Frequently asked questions
Can I take Disopyramide with Hawthorn?
MediHelp rates the interaction as moderate. Disopyramide and Hawthorn can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hawthorn has cardioactive properties and could theoretically modify the electrophysiologic effects of antiarrhythmics. Disopyramide has a narrow therapeutic window with proarrhythmic and negative inotropic risk.
How serious is the interaction between Disopyramide and Hawthorn?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and blood pressure if hawthorn is used with disopyramide, or advise avoiding the herb.
What other medicines interact with Hawthorn?
MediHelp also lists interactions of Hawthorn with, for example, Amiodarone, Digoxin, Encainide. The full list is on the Hawthorn page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
