Drug interactions
Hawthorn + Ibutilide
Severity: Moderate
Hawthorn and Ibutilide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has cardioactive properties and has been theoretically linked to QT effects. Ibutilide causes marked QT prolongation and torsades de pointes, so any additional effect is undesirable.
What this interaction means in plain words
Hawthorn and Ibutilide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hawthorn belongs to Gastrointestinal Tract; Ibutilide belongs to Cardiovascular.
Why it happens
Theoretical additive cardiac repolarization effects.
What to do
Avoid hawthorn around ibutilide administration and continue ECG monitoring per label.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Procainamide Moderate
- Hawthorn + Propranolol Moderate
Other interactions of Ibutilide
- Amiodarone + Ibutilide Contraindicated
- Amisulpride + Ibutilide Contraindicated
- Chlorpromazine + Ibutilide Contraindicated
- Clarithromycin + Ibutilide Contraindicated
- Desipramine + Ibutilide Contraindicated
- Dolasetron + Ibutilide Contraindicated
Frequently asked questions
Can I take Hawthorn with Ibutilide?
MediHelp rates the interaction as moderate. Hawthorn and Ibutilide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hawthorn has cardioactive properties and has been theoretically linked to QT effects. Ibutilide causes marked QT prolongation and torsades de pointes, so any additional effect is undesirable.
How serious is the interaction between Hawthorn and Ibutilide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid hawthorn around ibutilide administration and continue ECG monitoring per label.
What other medicines interact with Hawthorn?
MediHelp also lists interactions of Hawthorn with, for example, Amiodarone, Digoxin, Disopyramide. The full list is on the Hawthorn page.
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