Drug interactions
Clevidipine + Voriconazole
Severity: Minor
Clevidipine and Voriconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole may modestly raise clevidipine levels, but clevidipine is mainly cleared by blood and tissue esterases. The clinical effect is likely small, though excess hypotension is possible.
What this interaction means in plain words
Clevidipine and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clevidipine belongs to Cardiovascular; Voriconazole belongs to Anti Fungals.
Why it happens
Possible CYP3A4 inhibition, although clevidipine is mainly hydrolyzed by esterases.
What to do
Titrate clevidipine to blood pressure as usual and monitor for hypotension.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Other interactions of Clevidipine
Frequently asked questions
Can I take Clevidipine with Voriconazole?
MediHelp rates the interaction as minor. Clevidipine and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voriconazole may modestly raise clevidipine levels, but clevidipine is mainly cleared by blood and tissue esterases. The clinical effect is likely small, though excess hypotension is possible.
How serious is the interaction between Clevidipine and Voriconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate clevidipine to blood pressure as usual and monitor for hypotension.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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