Drug interactions
Clorazepate + Teduglutide
Severity: Minor
Clorazepate and Teduglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide improves intestinal fluid and nutrient absorption and may increase absorption of oral drugs. For clorazepate this could mean higher exposure and more sedation, though data specific to this drug are lacking.
What this interaction means in plain words
Clorazepate and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clorazepate belongs to Central Nervous System; Teduglutide belongs to Endocrine.
Why it happens
Increased intestinal absorption of oral drugs due to the intestinotrophic effect of teduglutide.
What to do
Monitor for increased sedation after teduglutide is started and reduce the clorazepate dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clorazepate
- Calcium / magnesium / potassium / sodium oxybates + Clorazepate Contraindicated
- Clorazepate + Sodium oxybate Contraindicated
- Alfentanil + Clorazepate Major
- Alprazolam + Clorazepate Major
- Amobarbital + Clorazepate Major
- Belladonna and opium + Clorazepate Major
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Clorazepate with Teduglutide?
MediHelp rates the interaction as minor. Clorazepate and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teduglutide improves intestinal fluid and nutrient absorption and may increase absorption of oral drugs. For clorazepate this could mean higher exposure and more sedation, though data specific to this drug are lacking.
How serious is the interaction between Clorazepate and Teduglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased sedation after teduglutide is started and reduce the clorazepate dose if needed.
What other medicines interact with Clorazepate?
MediHelp also lists interactions of Clorazepate with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Clorazepate page.
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