Drug interactions
Corticotropin + Furosemide
Severity: Moderate
Corticotropin and Furosemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticotropin stimulates adrenal corticosteroid production, which promotes potassium excretion, and furosemide also wastes potassium. Together they can cause hypokalemia and fluid shifts.
What this interaction means in plain words
Corticotropin and Furosemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Corticotropin belongs to Endocrine; Furosemide belongs to Cardiovascular.
Why it happens
Additive renal potassium loss from mineralocorticoid effect plus loop diuretic action.
What to do
Monitor serum potassium and magnesium during therapy and replace as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Other interactions of Corticotropin
Frequently asked questions
Can I take Corticotropin with Furosemide?
MediHelp rates the interaction as moderate. Corticotropin and Furosemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticotropin stimulates adrenal corticosteroid production, which promotes potassium excretion, and furosemide also wastes potassium. Together they can cause hypokalemia and fluid shifts.
How serious is the interaction between Corticotropin and Furosemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium during therapy and replace as needed.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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