Drug interactions
Cortisone + Silodosin
Severity: Minor
Cortisone and Silodosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cortisone is a weak CYP3A4 inducer at best, and any reduction in silodosin exposure is unlikely to be clinically meaningful.
What this interaction means in plain words
Cortisone and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak CYP3A4 induction by corticosteroids; not well established.
What to do
No routine action is needed. Review urinary symptom control if prolonged high-dose corticosteroid therapy is started.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Silodosin
- Atazanavir + Silodosin Contraindicated
- Conivaptan + Silodosin Contraindicated
- Darunavir + Silodosin Contraindicated
- Fosamprenavir + Silodosin Contraindicated
- Indinavir + Silodosin Contraindicated
- Itraconazole + Silodosin Contraindicated
Frequently asked questions
Can I take Cortisone with Silodosin?
MediHelp rates the interaction as minor. Cortisone and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cortisone is a weak CYP3A4 inducer at best, and any reduction in silodosin exposure is unlikely to be clinically meaningful.
How serious is the interaction between Cortisone and Silodosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Review urinary symptom control if prolonged high-dose corticosteroid therapy is started.
What other medicines interact with Silodosin?
MediHelp also lists interactions of Silodosin with, for example, Atazanavir, Conivaptan, Darunavir. The full list is on the Silodosin page.
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