Drug interactions
Dantrolene + Ramelteon
Severity: Minor
Dantrolene and Ramelteon: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ramelteon is a hypnotic that can cause next-day drowsiness, and dantrolene is also sedating. Together they may increase daytime sleepiness and impair alertness.
What this interaction means in plain words
Dantrolene and Ramelteon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dantrolene belongs to Musculoskeletal; Ramelteon belongs to Central Nervous System.
Why it happens
Additive central nervous system depressant effects.
What to do
Counsel patients about additive drowsiness and avoiding driving if impaired. Reassess the need for the hypnotic if daytime sedation occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dantrolene
Other interactions of Ramelteon
- Calcium / magnesium / potassium / sodium oxybates + Ramelteon Contraindicated
- Fluvoxamine + Ramelteon Contraindicated
- Ramelteon + Sodium oxybate Contraindicated
- Alfentanil + Ramelteon Moderate
- Amitriptyline + Ramelteon Moderate
- Amobarbital + Ramelteon Moderate
Frequently asked questions
Can I take Dantrolene with Ramelteon?
MediHelp rates the interaction as minor. Dantrolene and Ramelteon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ramelteon is a hypnotic that can cause next-day drowsiness, and dantrolene is also sedating. Together they may increase daytime sleepiness and impair alertness.
How serious is the interaction between Dantrolene and Ramelteon?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about additive drowsiness and avoiding driving if impaired. Reassess the need for the hypnotic if daytime sedation occurs.
What other medicines interact with Dantrolene?
MediHelp also lists interactions of Dantrolene with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Dantrolene page.
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