Drug interactions
Dapagliflozin-metformin + Tibolone
Severity: Minor
Dapagliflozin-metformin and Tibolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tibolone has hormonal activity that may modestly affect glucose tolerance, though it generally has little effect on glycaemic control. Any change in diabetic control is expected to be small.
What this interaction means in plain words
Dapagliflozin-metformin and Tibolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dapagliflozin-metformin belongs to Endocrine; Tibolone belongs to Endocrine.
Why it happens
Sex-steroid activity may slightly alter insulin sensitivity, a weak pharmacodynamic antagonism.
What to do
Routine glucose monitoring is sufficient; adjust antidiabetic therapy only if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Other interactions of Tibolone
- Amobarbital + Tibolone Moderate
- Carbamazepine + Tibolone Moderate
- Secobarbital + Tibolone Moderate
- Alogliptin-metformin + Tibolone Minor
- Argatroban + Tibolone Minor
- Empagliflozin-metformin + Tibolone Minor
Frequently asked questions
Can I take Dapagliflozin-metformin with Tibolone?
MediHelp rates the interaction as minor. Dapagliflozin-metformin and Tibolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tibolone has hormonal activity that may modestly affect glucose tolerance, though it generally has little effect on glycaemic control. Any change in diabetic control is expected to be small.
How serious is the interaction between Dapagliflozin-metformin and Tibolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Routine glucose monitoring is sufficient; adjust antidiabetic therapy only if control changes.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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