Drug interactions
Dapsone + Tazemetostat
Severity: Minor
Dapsone and Tazemetostat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tazemetostat is a weak-to-moderate CYP3A4 inducer and may lower dapsone exposure. Clinical consequence is likely modest.
What this interaction means in plain words
Dapsone and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dapsone belongs to Anti Bacterial; Tazemetostat belongs to Miscellaneous.
Why it happens
Tazemetostat induces CYP3A4, slightly increasing dapsone metabolism.
What to do
Monitor clinical response to dapsone; no empiric dose adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapsone
- Bcg vaccine live + Dapsone Major
- Dapsone + Primaquine Major
- Apalutamide + Dapsone Moderate
- Belzutifan + Dapsone Moderate
- Bosentan + Dapsone Moderate
- Bupivacaine implant + Dapsone Moderate
Other interactions of Tazemetostat
Frequently asked questions
Can I take Dapsone with Tazemetostat?
MediHelp rates the interaction as minor. Dapsone and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tazemetostat is a weak-to-moderate CYP3A4 inducer and may lower dapsone exposure. Clinical consequence is likely modest.
How serious is the interaction between Dapsone and Tazemetostat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to dapsone; no empiric dose adjustment is needed.
What other medicines interact with Dapsone?
MediHelp also lists interactions of Dapsone with, for example, Bcg vaccine live, Primaquine, Apalutamide. The full list is on the Dapsone page.
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