Drug interactions
Dasatinib + Indacaterol-glycopyrronium
Severity: Moderate
Dasatinib and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib has been associated with QT prolongation, and beta-2 agonists may add to arrhythmia risk, particularly with hypokalemia. The combination is relevant mostly in patients with other cardiac risk factors.
What this interaction means in plain words
Dasatinib and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dasatinib belongs to Oncology; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive QT prolongation and beta-adrenergic cardiac stimulation.
What to do
Correct hypokalemia and hypomagnesemia, and monitor ECG in patients with cardiac risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Dasatinib and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dasatinib has been associated with QT prolongation, and beta-2 agonists may add to arrhythmia risk, particularly with hypokalemia. The combination is relevant mostly in patients with other cardiac risk factors.
How serious is the interaction between Dasatinib and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct hypokalemia and hypomagnesemia, and monitor ECG in patients with cardiac risk factors.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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