Drug interactions
Daunorubicin + Oteseconazole
Severity: Minor
Daunorubicin and Oteseconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oteseconazole inhibits BCRP and may increase exposure to BCRP substrates. Daunorubicin toxicity such as myelosuppression could be enhanced, although clinical data are lacking.
What this interaction means in plain words
Daunorubicin and Oteseconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Daunorubicin belongs to Oncology; Oteseconazole belongs to Anti Fungals.
Why it happens
Oteseconazole inhibits BCRP efflux transport, potentially increasing daunorubicin exposure.
What to do
Monitor complete blood counts and signs of anthracycline toxicity. Consider a dose reduction of daunorubicin if adverse effects occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Daunorubicin
- Adenovirus types 4 and 7 live + Daunorubicin Contraindicated
- Belatacept + Daunorubicin Major
- Cyclosporine + Daunorubicin Major
- Cyclosporin + Daunorubicin Major
- Daunorubicin + Dengue vaccine Major
- Daunorubicin + Etrasimod Major
Other interactions of Oteseconazole
- Atorvastatin + Oteseconazole Moderate
- Fluvastatin + Oteseconazole Moderate
- Glibenclamide + Oteseconazole Moderate
- Glyburide-metformin + Oteseconazole Moderate
- Irinotecan + Oteseconazole Moderate
- Lapatinib + Oteseconazole Moderate
Frequently asked questions
Can I take Daunorubicin with Oteseconazole?
MediHelp rates the interaction as minor. Daunorubicin and Oteseconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oteseconazole inhibits BCRP and may increase exposure to BCRP substrates. Daunorubicin toxicity such as myelosuppression could be enhanced, although clinical data are lacking.
How serious is the interaction between Daunorubicin and Oteseconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts and signs of anthracycline toxicity. Consider a dose reduction of daunorubicin if adverse effects occur.
What other medicines interact with Daunorubicin?
MediHelp also lists interactions of Daunorubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclosporine. The full list is on the Daunorubicin page.
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