Drug interactions
Desflurane + Granisetron
Severity: Minor
Desflurane and Granisetron: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Volatile anesthetics such as desflurane can prolong the QT interval, and granisetron may add a small effect. The practical risk is low in patients without other risk factors.
What this interaction means in plain words
Desflurane and Granisetron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Desflurane belongs to Central Nervous System; Granisetron belongs to Gastrointestinal Tract.
Why it happens
Additive QT prolongation.
What to do
Correct electrolytes before anesthesia and monitor the ECG in patients with long QT or other QT-prolonging drugs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Granisetron
- Apomorphine + Granisetron Contraindicated
- Amiodarone + Granisetron Major
- Amisulpride + Granisetron Major
- Arsenic trioxide + Granisetron Major
- Artemether / lumefantrine + Granisetron Major
- Artemether + Granisetron Major
Other interactions of Desflurane
Frequently asked questions
Can I take Desflurane with Granisetron?
MediHelp rates the interaction as minor. Desflurane and Granisetron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Volatile anesthetics such as desflurane can prolong the QT interval, and granisetron may add a small effect. The practical risk is low in patients without other risk factors.
How serious is the interaction between Desflurane and Granisetron?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct electrolytes before anesthesia and monitor the ECG in patients with long QT or other QT-prolonging drugs.
What other medicines interact with Granisetron?
MediHelp also lists interactions of Granisetron with, for example, Apomorphine, Amiodarone, Amisulpride. The full list is on the Granisetron page.
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