Drug interactions
Desflurane + Papaverine
Severity: Minor
Desflurane and Papaverine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Papaverine is a vasodilator and smooth muscle relaxant with little clinically meaningful sedative action. Any interaction is likely limited to additive hypotension rather than sedation.
What this interaction means in plain words
Desflurane and Papaverine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Desflurane belongs to Central Nervous System; Papaverine belongs to Cardiovascular.
Why it happens
Possible additive vasodilation and blood pressure lowering; a sedative interaction is not established.
What to do
Monitor blood pressure during anesthesia when papaverine is given, and treat hypotension as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Desflurane
Other interactions of Papaverine
- Givinostat + Papaverine Major
- Bretylium + Papaverine Moderate
- Calcium / magnesium / potassium / sodium oxybates + Papaverine Moderate
- Carbidopa-entacapone-levodopa + Papaverine Moderate
- Carbidopa-levodopa + Papaverine Moderate
- Carbidopa + Papaverine Moderate
Frequently asked questions
Can I take Desflurane with Papaverine?
MediHelp rates the interaction as minor. Desflurane and Papaverine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Papaverine is a vasodilator and smooth muscle relaxant with little clinically meaningful sedative action. Any interaction is likely limited to additive hypotension rather than sedation.
How serious is the interaction between Desflurane and Papaverine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during anesthesia when papaverine is given, and treat hypotension as needed.
What other medicines interact with Desflurane?
MediHelp also lists interactions of Desflurane with, for example, Amisulpride, Anagrelide, Arsenic trioxide. The full list is on the Desflurane page.
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