Drug interactions
Desogestrel + Liraglutide
Severity: Minor
Desogestrel and Liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hormonal contraceptives containing desogestrel can slightly impair glucose tolerance, which may weaken glycemic control in diabetic patients taking liraglutide. The effect is generally small with modern low-dose products.
What this interaction means in plain words
Desogestrel and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Desogestrel belongs to Endocrine; Liraglutide belongs to Endocrine.
Why it happens
Pharmacodynamic antagonism through modest progestin and estrogen effects on insulin sensitivity.
What to do
Monitor glycemic control when the contraceptive is started or stopped. Adjust the antidiabetic regimen only if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Liraglutide
Other interactions of Desogestrel
- Carbamazepine + Desogestrel Major
- Berotralstat + Desogestrel Moderate
- Desogestrel + Lamotrigine Moderate
- Desogestrel + Mifepristone Moderate
- Desogestrel + Warfarin Moderate
- Alogliptin-metformin + Desogestrel Minor
Frequently asked questions
Can I take Desogestrel with Liraglutide?
MediHelp rates the interaction as minor. Desogestrel and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hormonal contraceptives containing desogestrel can slightly impair glucose tolerance, which may weaken glycemic control in diabetic patients taking liraglutide. The effect is generally small with modern low-dose products.
How serious is the interaction between Desogestrel and Liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glycemic control when the contraceptive is started or stopped. Adjust the antidiabetic regimen only if control changes.
What other medicines interact with Liraglutide?
MediHelp also lists interactions of Liraglutide with, for example, Insulin degludec-liraglutide, Insulin glargine-lixisenatide, Alogliptin-metformin. The full list is on the Liraglutide page.
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