Drug interactions
Dexchlorpheniramine + Nabilone
Severity: Moderate
Dexchlorpheniramine and Nabilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexchlorpheniramine is a sedating first-generation antihistamine with anticholinergic effects. With nabilone it can increase drowsiness, dizziness and impair concentration and driving ability.
What this interaction means in plain words
Dexchlorpheniramine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dexchlorpheniramine belongs to Respiratory; Nabilone belongs to Gastrointestinal Tract.
Why it happens
Additive central nervous system depression with anticholinergic contribution.
What to do
Counsel on sedation and avoid driving; consider a non-sedating antihistamine if appropriate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Other interactions of Dexchlorpheniramine
- Alprazolam + Dexchlorpheniramine Moderate
- Amisulpride + Dexchlorpheniramine Moderate
- Amitriptyline + Dexchlorpheniramine Moderate
- Amobarbital + Dexchlorpheniramine Moderate
- Asenapine + Dexchlorpheniramine Moderate
- Azelastine-fluticasone + Dexchlorpheniramine Moderate
Frequently asked questions
Can I take Dexchlorpheniramine with Nabilone?
MediHelp rates the interaction as moderate. Dexchlorpheniramine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexchlorpheniramine is a sedating first-generation antihistamine with anticholinergic effects. With nabilone it can increase drowsiness, dizziness and impair concentration and driving ability.
How serious is the interaction between Dexchlorpheniramine and Nabilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on sedation and avoid driving; consider a non-sedating antihistamine if appropriate.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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