Drug interactions
Dexmedetomidine + Flibanserin
Severity: Moderate
Dexmedetomidine and Flibanserin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexmedetomidine is a sedative and sympatholytic that causes hypotension and bradycardia, so combined use with flibanserin may deepen sedation and hypotension. Flibanserin labeling cautions about additive CNS depression.
What this interaction means in plain words
Dexmedetomidine and Flibanserin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dexmedetomidine belongs to Central Nervous System; Flibanserin belongs to Genitourinary.
Why it happens
Additive CNS depressant and hypotensive effects.
What to do
Monitor sedation level, blood pressure and heart rate during dexmedetomidine use. Consider holding flibanserin around procedural sedation.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Other interactions of Dexmedetomidine
Frequently asked questions
Can I take Dexmedetomidine with Flibanserin?
MediHelp rates the interaction as moderate. Dexmedetomidine and Flibanserin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexmedetomidine is a sedative and sympatholytic that causes hypotension and bradycardia, so combined use with flibanserin may deepen sedation and hypotension. Flibanserin labeling cautions about additive CNS depression.
How serious is the interaction between Dexmedetomidine and Flibanserin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation level, blood pressure and heart rate during dexmedetomidine use. Consider holding flibanserin around procedural sedation.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
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