Drug interactions
Dicloxacillin + Mycophenolate mofetil
Severity: Minor
Dicloxacillin and Mycophenolate mofetil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antibacterials that alter gut flora, such as penicillins, may lower exposure to mycophenolic acid. This could reduce immunosuppression and raise the risk of rejection, although the effect is not well established for dicloxacillin.
What this interaction means in plain words
Dicloxacillin and Mycophenolate mofetil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dicloxacillin belongs to Anti Bacterial; Mycophenolate mofetil belongs to Miscellaneous.
Why it happens
Possible reduction of enterohepatic recirculation of mycophenolic acid through changes in intestinal flora that deconjugate its glucuronide.
What to do
No routine dose change is needed; watch for signs of reduced immunosuppression during and after a course of dicloxacillin. Consider mycophenolic acid level monitoring if rejection is suspected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Other interactions of Dicloxacillin
- Dicloxacillin + Phenindione Major
- Atogepant + Dicloxacillin Moderate
- Axitinib + Dicloxacillin Moderate
- Bcg vaccine live + Dicloxacillin Moderate
- Cholera vaccine + Dicloxacillin Moderate
- Demeclocycline + Dicloxacillin Moderate
Frequently asked questions
Can I take Dicloxacillin with Mycophenolate mofetil?
MediHelp rates the interaction as minor. Dicloxacillin and Mycophenolate mofetil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antibacterials that alter gut flora, such as penicillins, may lower exposure to mycophenolic acid. This could reduce immunosuppression and raise the risk of rejection, although the effect is not well established for dicloxacillin.
How serious is the interaction between Dicloxacillin and Mycophenolate mofetil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; watch for signs of reduced immunosuppression during and after a course of dicloxacillin. Consider mycophenolic acid level monitoring if rejection is suspected.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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