Drug interactions
Dicyclomine + Indacaterol-glycopyrronium
Severity: Moderate
Dicyclomine and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dicyclomine is an antimuscarinic antispasmodic, and combining it with glycopyrronium may increase dry mouth, constipation, urinary retention and tachycardia. Inhaled systemic exposure is low, so effects are generally mild.
What this interaction means in plain words
Dicyclomine and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dicyclomine belongs to Respiratory; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for anticholinergic effects and reduce the dicyclomine dose if they occur. Use extra care in patients with glaucoma or urinary retention.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Dicyclomine
- Clozapine + Dicyclomine Major
- Dicyclomine + Henbane Major
- Dicyclomine + Imipramine Major
- Dicyclomine + Pramlintide Major
- Abobotulinumtoxina + Dicyclomine Moderate
- Aclidinium + Dicyclomine Moderate
Frequently asked questions
Can I take Dicyclomine with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Dicyclomine and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dicyclomine is an antimuscarinic antispasmodic, and combining it with glycopyrronium may increase dry mouth, constipation, urinary retention and tachycardia. Inhaled systemic exposure is low, so effects are generally mild.
How serious is the interaction between Dicyclomine and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects and reduce the dicyclomine dose if they occur. Use extra care in patients with glaucoma or urinary retention.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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