Drug interactions
Dicyclomine + Succinylcholine
Severity: Minor
Dicyclomine and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Succinylcholine is a depolarizing nicotinic agonist that can cause bradycardia, and anticholinergics are often used to counter this. Dicyclomine is not expected to change neuromuscular blockade significantly, so any interaction is minor.
What this interaction means in plain words
Dicyclomine and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dicyclomine belongs to Respiratory; Succinylcholine belongs to Musculoskeletal.
Why it happens
Muscarinic blockade may offset succinylcholine-related bradycardia; no established effect on neuromuscular blockade.
What to do
No dose adjustment is needed. Monitor heart rate and rhythm during anesthesia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dicyclomine
- Clozapine + Dicyclomine Major
- Dicyclomine + Henbane Major
- Dicyclomine + Imipramine Major
- Dicyclomine + Pramlintide Major
- Abobotulinumtoxina + Dicyclomine Moderate
- Aclidinium + Dicyclomine Moderate
Other interactions of Succinylcholine
Frequently asked questions
Can I take Dicyclomine with Succinylcholine?
MediHelp rates the interaction as minor. Dicyclomine and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Succinylcholine is a depolarizing nicotinic agonist that can cause bradycardia, and anticholinergics are often used to counter this. Dicyclomine is not expected to change neuromuscular blockade significantly, so any interaction is minor.
How serious is the interaction between Dicyclomine and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Monitor heart rate and rhythm during anesthesia.
What other medicines interact with Dicyclomine?
MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.
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