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Drug interactions

Digoxin + Formoterol-mometasone

Severity: Moderate

Digoxin and Formoterol-mometasone: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Formoterol can lower serum potassium and may cause tachyarrhythmias, and hypokalemia increases sensitivity to digoxin toxicity. This may raise the risk of digoxin-related arrhythmias.

What this interaction means in plain words

Digoxin and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Digoxin belongs to Cardiovascular; Formoterol-mometasone belongs to Respiratory.

Evidence level: Moderate

Why it happens

Beta-2 agonist-induced hypokalemia potentiates digoxin proarrhythmic effects.

What to do

Monitor serum potassium and digoxin levels, and ECG if symptoms occur. Correct hypokalemia promptly.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Digoxin with Formoterol-mometasone?

MediHelp rates the interaction as moderate. Digoxin and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Formoterol can lower serum potassium and may cause tachyarrhythmias, and hypokalemia increases sensitivity to digoxin toxicity. This may raise the risk of digoxin-related arrhythmias.

How serious is the interaction between Digoxin and Formoterol-mometasone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and digoxin levels, and ECG if symptoms occur. Correct hypokalemia promptly.

What other medicines interact with Formoterol-mometasone?

MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.

Full monographs, dosing and an interaction checker in the MediHelp app

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