Drug interactions
Diltiazem + Hawthorn
Severity: Minor
Diltiazem and Hawthorn: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has vasodilating and mild negative chronotropic properties that may add to diltiazem and cause hypotension or bradycardia. Clinical data are limited.
What this interaction means in plain words
Diltiazem and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Diltiazem belongs to Cardiovascular; Hawthorn belongs to Gastrointestinal Tract.
Why it happens
Additive vasodilatory and cardiac effects; the mechanism is not well established.
What to do
Ask patients about herbal use and monitor blood pressure and heart rate if hawthorn is continued.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Diltiazem
- Diltiazem + Flibanserin Contraindicated
- Diltiazem + Ivabradine Contraindicated
- Diltiazem + Lomitapide Contraindicated
- Diltiazem + Lonafarnib Contraindicated
- Acebutolol + Diltiazem Major
- Alfentanil + Diltiazem Major
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Diltiazem with Hawthorn?
MediHelp rates the interaction as minor. Diltiazem and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn has vasodilating and mild negative chronotropic properties that may add to diltiazem and cause hypotension or bradycardia. Clinical data are limited.
How serious is the interaction between Diltiazem and Hawthorn?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and monitor blood pressure and heart rate if hawthorn is continued.
What other medicines interact with Diltiazem?
MediHelp also lists interactions of Diltiazem with, for example, Flibanserin, Ivabradine, Lomitapide. The full list is on the Diltiazem page.
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