Drug interactions
Dipyridamole + Verteporfin
Severity: Minor
Dipyridamole and Verteporfin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole has been proposed to reduce the effect of verteporfin photodynamic therapy by limiting the vascular damage needed for efficacy. The clinical relevance is unclear, and verteporfin labeling mentions antiplatelet and vasodilating agents only as a theoretical concern.
What this interaction means in plain words
Dipyridamole and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.
Why it happens
Antiplatelet and vasodilatory effects may reduce photoactivated verteporfin-induced vascular occlusion; the mechanism is not well established.
What to do
No routine change is needed; consider the possibility of reduced response if verteporfin treatment seems less effective. Review the need for dipyridamole around the treatment session if clinically feasible.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Verteporfin
- Doxycycline + Verteporfin Moderate
- Griseofulvin + Verteporfin Moderate
- Minocycline + Verteporfin Moderate
- Tetracycline + Verteporfin Moderate
- Adapalene + Verteporfin Minor
- Amlodipine-hydrochlorothiazide-valsartan + Verteporfin Minor
Frequently asked questions
Can I take Dipyridamole with Verteporfin?
MediHelp rates the interaction as minor. Dipyridamole and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dipyridamole has been proposed to reduce the effect of verteporfin photodynamic therapy by limiting the vascular damage needed for efficacy. The clinical relevance is unclear, and verteporfin labeling mentions antiplatelet and vasodilating agents only as a theoretical concern.
How serious is the interaction between Dipyridamole and Verteporfin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; consider the possibility of reduced response if verteporfin treatment seems less effective. Review the need for dipyridamole around the treatment session if clinically feasible.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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