Drug interactions
Dolasetron + Formoterol-mometasone
Severity: Moderate
Dolasetron and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dolasetron's active metabolite prolongs the QT interval, and formoterol can add to this effect. Together they may increase the risk of serious ventricular arrhythmia.
What this interaction means in plain words
Dolasetron and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dolasetron belongs to Gastrointestinal Tract; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT prolongation, with possible beta2-agonist-induced hypokalemia.
What to do
Check potassium and magnesium and obtain an ECG in patients with cardiac risk factors. Consider an antiemetic with less QT effect if risk is high.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Dolasetron
- Apomorphine + Dolasetron Contraindicated
- Dofetilide + Dolasetron Contraindicated
- Dolasetron + Ibutilide Contraindicated
- Dolasetron + Pimozide Contraindicated
- Dolasetron + Thioridazine Contraindicated
- Dolasetron + Vandetanib Contraindicated
Frequently asked questions
Can I take Dolasetron with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Dolasetron and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dolasetron's active metabolite prolongs the QT interval, and formoterol can add to this effect. Together they may increase the risk of serious ventricular arrhythmia.
How serious is the interaction between Dolasetron and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and obtain an ECG in patients with cardiac risk factors. Consider an antiemetic with less QT effect if risk is high.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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