Drug interactions
Dopamine + Ipratropium-salbutamol
Severity: Moderate
Dopamine and Ipratropium-salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dopamine stimulates adrenergic and dopaminergic receptors, and with salbutamol it can intensify tachycardia, arrhythmias and blood pressure changes. Patients with cardiac disease are most at risk.
What this interaction means in plain words
Dopamine and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dopamine belongs to Cardiovascular; Ipratropium-salbutamol belongs to Respiratory.
Why it happens
Additive sympathomimetic effects on cardiac beta receptors.
What to do
Monitor ECG, heart rate and blood pressure continuously during dopamine infusion. Use the lowest effective salbutamol dose and reduce it if arrhythmias occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Dopamine
- Dihydroergotamine intranasal + Dopamine Contraindicated
- Dihydroergotamine + Dopamine Contraindicated
- Dopamine + Promethazine Contraindicated
- Dopamine + Selegiline transdermal Contraindicated
- Amitriptyline + Dopamine Major
- Clomipramine + Dopamine Major
Frequently asked questions
Can I take Dopamine with Ipratropium-salbutamol?
MediHelp rates the interaction as moderate. Dopamine and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dopamine stimulates adrenergic and dopaminergic receptors, and with salbutamol it can intensify tachycardia, arrhythmias and blood pressure changes. Patients with cardiac disease are most at risk.
How serious is the interaction between Dopamine and Ipratropium-salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate and blood pressure continuously during dopamine infusion. Use the lowest effective salbutamol dose and reduce it if arrhythmias occur.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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