Drug interactions
Dopamine + Oxytocin
Severity: Moderate
Dopamine and Oxytocin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxytocin can cause hypotension at higher doses, whereas vasopressors given with it may produce severe hypertension. Labeling for oxytocin warns of severe hypertension when it follows vasoconstrictor use, so blood pressure may become unpredictable.
What this interaction means in plain words
Dopamine and Oxytocin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dopamine belongs to Cardiovascular; Oxytocin belongs to Endocrine.
Why it happens
Additive pharmacodynamic effects on vascular tone and blood pressure.
What to do
Monitor blood pressure and heart rate continuously and titrate dopamine and oxytocin infusions to response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dopamine
- Dihydroergotamine intranasal + Dopamine Contraindicated
- Dihydroergotamine + Dopamine Contraindicated
- Dopamine + Promethazine Contraindicated
- Dopamine + Selegiline transdermal Contraindicated
- Amitriptyline + Dopamine Major
- Clomipramine + Dopamine Major
Other interactions of Oxytocin
- Carboprost tromethamine + Oxytocin Major
- Dinoprostone + Oxytocin Major
- Ephedrine + Oxytocin Major
- Fexinidazole + Oxytocin Major
- Givinostat + Oxytocin Major
- Misoprostol + Oxytocin Major
Frequently asked questions
Can I take Dopamine with Oxytocin?
MediHelp rates the interaction as moderate. Dopamine and Oxytocin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxytocin can cause hypotension at higher doses, whereas vasopressors given with it may produce severe hypertension. Labeling for oxytocin warns of severe hypertension when it follows vasoconstrictor use, so blood pressure may become unpredictable.
How serious is the interaction between Dopamine and Oxytocin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate continuously and titrate dopamine and oxytocin infusions to response.
What other medicines interact with Dopamine?
MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine intranasal, Dihydroergotamine, Promethazine. The full list is on the Dopamine page.
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