Drug interactions
Doxycycline + Ferric maltol
Severity: Moderate
Doxycycline and Ferric maltol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron in ferric maltol can bind doxycycline in the gut, reducing its absorption, and doxycycline may also reduce iron uptake. This can lead to antibiotic treatment failure.
What this interaction means in plain words
Doxycycline and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxycycline belongs to Anti Bacterial; Ferric maltol belongs to Miscellaneous.
Why it happens
Chelation between ferric iron and doxycycline in the gastrointestinal tract reduces absorption of the antibiotic.
What to do
Separate doses, giving doxycycline at least 2 hours before or 3 to 4 hours after ferric maltol. Monitor clinical response to the antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Doxycycline
- Acitretin + Doxycycline Contraindicated
- Aminolevulinic acid + Doxycycline Major
- Cholera vaccine + Doxycycline Major
- Doxycycline + Isotretinoin Major
- Doxycycline + Methoxyflurane Major
- Doxycycline + Microbiota Major
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Frequently asked questions
Can I take Doxycycline with Ferric maltol?
MediHelp rates the interaction as moderate. Doxycycline and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron in ferric maltol can bind doxycycline in the gut, reducing its absorption, and doxycycline may also reduce iron uptake. This can lead to antibiotic treatment failure.
How serious is the interaction between Doxycycline and Ferric maltol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses, giving doxycycline at least 2 hours before or 3 to 4 hours after ferric maltol. Monitor clinical response to the antibiotic.
What other medicines interact with Doxycycline?
MediHelp also lists interactions of Doxycycline with, for example, Acitretin, Aminolevulinic acid, Cholera vaccine. The full list is on the Doxycycline page.
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