Drug interactions
Elagolix + Ifosfamide
Severity: Minor
Elagolix and Ifosfamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak-to-moderate CYP3A4 inducer and could modestly increase ifosfamide metabolism. The clinical significance is uncertain, and elagolix is not typically used alongside ifosfamide chemotherapy.
What this interaction means in plain words
Elagolix and Ifosfamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elagolix belongs to Musculoskeletal; Ifosfamide belongs to Oncology.
Why it happens
Elagolix weakly induces CYP3A4, potentially increasing ifosfamide metabolism.
What to do
No routine adjustment is needed; monitor for altered ifosfamide response or neurotoxicity if used together.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine live Contraindicated
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contraindicated
- Ifosfamide + Measles vaccine Contraindicated
- Ifosfamide + Rotavirus oral vaccine live Contraindicated
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Elagolix with Ifosfamide?
MediHelp rates the interaction as minor. Elagolix and Ifosfamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak-to-moderate CYP3A4 inducer and could modestly increase ifosfamide metabolism. The clinical significance is uncertain, and elagolix is not typically used alongside ifosfamide chemotherapy.
How serious is the interaction between Elagolix and Ifosfamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; monitor for altered ifosfamide response or neurotoxicity if used together.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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