Drug interactions
Eltrombopag + Ferric maltol
Severity: Moderate
Eltrombopag and Ferric maltol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron preparations contain polyvalent cations that can bind eltrombopag in the gut and lower its exposure, potentially reducing platelet response.
What this interaction means in plain words
Eltrombopag and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eltrombopag belongs to Miscellaneous; Ferric maltol belongs to Miscellaneous.
Why it happens
Iron cations chelate eltrombopag in the gastrointestinal tract, reducing absorption.
What to do
Give eltrombopag at least 2 hours before or 4 hours after ferric maltol. Monitor platelet counts.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eltrombopag
- Alpelisib + Eltrombopag Moderate
- Aluminum hydroxide + Eltrombopag Moderate
- Amobarbital + Eltrombopag Moderate
- Artesunate + Eltrombopag Moderate
- Atazanavir + Eltrombopag Moderate
- Atorvastatin + Eltrombopag Moderate
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Frequently asked questions
Can I take Eltrombopag with Ferric maltol?
MediHelp rates the interaction as moderate. Eltrombopag and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron preparations contain polyvalent cations that can bind eltrombopag in the gut and lower its exposure, potentially reducing platelet response.
How serious is the interaction between Eltrombopag and Ferric maltol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give eltrombopag at least 2 hours before or 4 hours after ferric maltol. Monitor platelet counts.
What other medicines interact with Eltrombopag?
MediHelp also lists interactions of Eltrombopag with, for example, Alpelisib, Aluminum hydroxide, Amobarbital. The full list is on the Eltrombopag page.
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