Drug interactions
Hawthorn + Propranolol
Severity: Moderate
Hawthorn and Propranolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has vasodilating and mild negative chronotropic and positive inotropic activity, so it may add to the blood pressure and heart rate lowering of propranolol. Evidence is limited and the product content varies.
What this interaction means in plain words
Hawthorn and Propranolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hawthorn belongs to Gastrointestinal Tract; Propranolol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic cardiovascular effects; the mechanism is not firmly established.
What to do
Ask patients about herbal use and monitor blood pressure and pulse if hawthorn is taken with propranolol. Discourage use unless supervised.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Albuterol + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Hawthorn with Propranolol?
MediHelp rates the interaction as moderate. Hawthorn and Propranolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hawthorn has vasodilating and mild negative chronotropic and positive inotropic activity, so it may add to the blood pressure and heart rate lowering of propranolol. Evidence is limited and the product content varies.
How serious is the interaction between Hawthorn and Propranolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and monitor blood pressure and pulse if hawthorn is taken with propranolol. Discourage use unless supervised.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
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