Drug interactions
Entecavir + Mesalamine
Severity: Minor
Entecavir and Mesalamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Entecavir is eliminated by glomerular filtration and tubular secretion, so drugs that impair kidney function or compete for secretion can raise its levels. Mesalamine has rarely been associated with nephrotoxicity, so combined use warrants some attention to renal function.
What this interaction means in plain words
Entecavir and Mesalamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Entecavir belongs to Anti Virals; Mesalamine belongs to Gastrointestinal Tract.
Why it happens
Possible competition for renal tubular secretion and additive effects on renal function.
What to do
Monitor renal function periodically and adjust the entecavir dose if creatinine clearance falls.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mesalamine
Other interactions of Entecavir
Frequently asked questions
Can I take Entecavir with Mesalamine?
MediHelp rates the interaction as minor. Entecavir and Mesalamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Entecavir is eliminated by glomerular filtration and tubular secretion, so drugs that impair kidney function or compete for secretion can raise its levels. Mesalamine has rarely been associated with nephrotoxicity, so combined use warrants some attention to renal function.
How serious is the interaction between Entecavir and Mesalamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function periodically and adjust the entecavir dose if creatinine clearance falls.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
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