Drug interactions
Eprosartan-hydrochlorothiazide + Maraviroc
Severity: Moderate
Eprosartan-hydrochlorothiazide and Maraviroc: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, and combining it with eprosartan and hydrochlorothiazide may increase dizziness, syncope and falls. Volume depletion from the diuretic may add to the risk.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eprosartan-hydrochlorothiazide belongs to Cardiovascular; Maraviroc belongs to Anti Virals.
Why it happens
Additive blood pressure lowering and orthostatic effects.
What to do
Monitor blood pressure, including orthostatic readings, and counsel patients to rise slowly. Reduce antihypertensive doses if symptomatic hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Maraviroc?
MediHelp rates the interaction as moderate. Eprosartan-hydrochlorothiazide and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension, and combining it with eprosartan and hydrochlorothiazide may increase dizziness, syncope and falls. Volume depletion from the diuretic may add to the risk.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Maraviroc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, including orthostatic readings, and counsel patients to rise slowly. Reduce antihypertensive doses if symptomatic hypotension develops.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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