Drug interactions
Ertugliflozin-sitagliptin + Indapamide
Severity: Minor
Ertugliflozin-sitagliptin and Indapamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indapamide is a thiazide-like diuretic that may modestly raise glucose and add to volume depletion with ertugliflozin. The glycemic effect is generally small at usual doses.
What this interaction means in plain words
Ertugliflozin-sitagliptin and Indapamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ertugliflozin-sitagliptin belongs to Endocrine; Indapamide belongs to Cardiovascular.
Why it happens
Diuretic-induced hypokalemia may reduce insulin secretion, and combined diuretic effects add to volume loss.
What to do
Monitor blood glucose, blood pressure and electrolytes after starting indapamide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ertugliflozin-sitagliptin
Other interactions of Indapamide
Frequently asked questions
Can I take Ertugliflozin-sitagliptin with Indapamide?
MediHelp rates the interaction as minor. Ertugliflozin-sitagliptin and Indapamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Indapamide is a thiazide-like diuretic that may modestly raise glucose and add to volume depletion with ertugliflozin. The glycemic effect is generally small at usual doses.
How serious is the interaction between Ertugliflozin-sitagliptin and Indapamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose, blood pressure and electrolytes after starting indapamide.
What other medicines interact with Ertugliflozin-sitagliptin?
MediHelp also lists interactions of Ertugliflozin-sitagliptin with, for example, Albiglutide, Aripiprazole, Asenapine. The full list is on the Ertugliflozin-sitagliptin page.
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